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Curcuminoids, the bioactive components of the spice turmeric, were effective in alleviating the pain associated with knee osteoarthritis (OA), an Iranian pilot study found.
On the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) pain index, patients randomized to receive curcuminoids had baseline scores of 9.9, which decreased to 6.1 after 6 weeks of treatment, according to Ali-Reza Rahimnia, MD, of Baqiyatallah University in Tehran, and colleagues.
In contrast, those given placebo had scores of 10.5 at baseline and 9.4 at 6 weeks, the researchers reported online in Phytotherapy Research.
The treatment consisted of a proprietary formulation of curcuminoids (C3 Complex) 1,500 mg per day or placebo, and participants were allowed to use naproxen if necessary.
“In recent years, there has been a surge of interest to find herbal remedies for OA owing to the strong ethnobotanical evidence and identified analgesic, anti-inflammatory, and muscle relaxant properties for such therapies,” they wrote.
Turmeric has been widely used for various inflammatory conditions in traditional Asian medicine, and while considerable research into its bioactive properties exists, few clinical studies have been done.
Tags: turmeric, osteoarthritis, curcuminoids, herbal remedies, analgesic, anti-inflammatory, muscle relaxant