VascuStatin Formula is a water extraction of the leaves of the herb Convolvulus arvensis, commonly known as field bindweed. A key component of VascuStatin Formula's field bindweed extract is its proteoglycan mixture (PGM). In combination with proper nutrition, VascuStatin Formula may enhance the immune system's ability to maintain good health.
Native Americans have traditionally used plants like bindweed to support the health of the skin, which was especially important under the harsher living conditions of times past. Although we do not know of modern research supporting this use of field bindweed, we recognize that field bindweed's traditional value may have involved its component proteoglycans.
Recent research suggests that PGM has potent immune stimulating properties. In a recent in vitro study, lymphocyte proliferation and phagocyte activity increased with PGM administration. Through range of concentration medium of 0 to 100 mcg/ml of PGM, lymphocyte proliferation and activity increased 46 to 85%, respectively. Another study used the chicken egg chorio-allantoic membrane assay to study PGM regarding vascularization.
PGM's activity may depend upon its ability to change the biological balance between specific cytokines, such as interleukin 8 and platelet activating factor 4. Excess secretion of cytokines from specific cells can speed their neovascularization and growth. Proteoglycan proteins can bind and inactivate the above mentioned cytokines. In our review of the properties of PGM, it appears to be an effective support of the body's own immune defenses.
The bindweed used as the source of the PGM in VascuStatin Formula is grown in Wyoming. It is a non-toxic extract, as the toxic alkaloids are removed by a proprietary process.