Vitamin C (ascorbic acid) has numerous biological functions. Foremost, it is essential for the synthesis of collagen and glycosaminoglycans which are thebuilding materials of all connective tissues, such as skin, blood vessels, tendons, joint cartilage and bone.Vitamin C is the required coenzyme for two groups of enzymes that catalyze the crosslinking of collagenfibers - lysyl hydroxylases and prolyl hydroxylases. As such, vitamin C is essential for normal woundhealing and capillary health. It also participates in the biosynthesis of carnitine, serotonin and certainneurotransmitters, including norepinephrine.
Vitamin C is among the most powerful antioxidantsin humans and animals. It is a water-soluble, chainbreaking antioxidant that reacts directly withsuperoxide, hydroxyl radicals, and singlet oxygen. Laboratory studies show that vitamin C completelyprotects lipids in plasma and low-density lipoprotein (LDL) against atherogenic peroxidative damage. Inaddition, vitamin C interacts with glutathione and alpha-lipoic acid, and regenerates vitamin E. Theantioxidant functions of vitamin C appear to have clinical significance in providing protection from freeradical damage to the eyes, lungs, blood and the immune system.
L-Lysine is required for collagen cross-linking. Collagen cross-linking is important for resiliency andelasticity of the collagen and elastin present in all connective tissues and blood vessel walls. Duringformation of new collagen, fibroblasts secrete immature collagen strands and a vitamin C- and copper-requiringenzyme, lysyl oxidase. Lysyl oxidase oxidizes the free amino group of the immature collagen's lysyl sidechains. Once oxidized, these lysyl side chains spontaneously engage in various reactions betweencollagen strands to bring about cross-linking. As a result, a complex network of collagen strands isformed, providing elasticity and resiliency. L- L-Lysine has also been shown to be effective insupporting the immune system.
Adults take 2 capsules twice daily with meals or asdirected by physician.