The adult human body contains approximately 1,200g of calcium, of which about 99% is present in the skeleton, and 20-30 g of magnesium with about 60%located in bone. The remaining 1% of total body calcium and 40% of total body magnesium are foundin the soft tissues and play important roles in such vital functions as nerve conduction, musclecontraction, energy metabolism, blood clotting, membrane permeability and hormonal signaling.Blood calcium levels are carefully maintained within very narrow limits by the interplay of severalhormones (1,25-dihydroxy-cholecalciferol,parathyroid hormone, calcitonin, estrogen, andtestosterone) which control calcium absorption and excretion, as well as bone metabolism. Theintracellular levels of magnesium are also very tightly regulated, since their alterations can have profoundeffects on cardiac and skeletal muscle physiology. Intestinal calcium absorption ranges from 15 to 75%of ingested calcium. Adequate vitamin D status is necessary for normal calcium absorption.Magnesium absorption is independent of vitamin D status and ranges from 30 to 60% of ingestedmagnesium.
Bone is constantly turning over, through a continuousprocess of formation and resorption. In children and adolescents, the rate of formation of bone mineralpredominates over the rate of resorption. In later life, resorption predominates over formation. Therefore,in normal aging, there is a gradual loss of bone. Osteoporosis afflicts a large proportion of the elderlyin developed countries. Caucasian and Asian women typically have low peak bone densities, and aretherefore at the greatest risk of developing osteoporosis. It is generally accepted that obtainingenough dietary calcium throughout life can significantly decrease the risk of developingosteoporosis. Among other factors, such as regular exercise, gender and race, calcium supplementationduring childhood and adolescence appears to be a prerequisite for maintaining adequate bone densitylater in life. But even elderly osteoporotic patients can benefit significantly from supplementation withdietary calcium and magnesium.
Calcigard One-to-One provides highly beneficialsources of both calcium and magnesium. They are well absorbed and well tolerated.
Vitamin D is a key regulatory hormone for calcium and bone metabolism. Adequate vitamin D intake isimportant for ensuring normal calcium absorption and maintaining proper calcium plasma levels.People living in southern regions of the U.S. can derive significant amounts of vitamin D fromsunlight dependent synthesis in the skin during the summer, whereas people in the northern states haveto rely more on foods and supplements for adequate vitamin D status. This is why Calcigard formulas areavailable both with and without vitamin D.
Calcigard One-to-One: One to four tablets daily as adietary supplement, or as directed by a physician.
Take with food.