Description:
Phosphatidylcholine, or PC, is a polar lipid molecule that is anaturally occurring, integral component of the cellularmembrane, adding fluidity and strength to cells. PC serves asa source of choline, an important nutrient for liver functionand a precursor of the neurotransmitter acetylcholine. Dietarysources of PC include soy lecithin.Pure Encapsulations Phosphatidylcholine is derived fromsoy lecithin, a source that is rich in polyunsaturated fattyacids, as opposed to animal-derived sources, which tendto be much higher in saturated fatty acids. There is nodetectable GMO material in this product. Health Functions:
Liver Health: In a multi-centered, randomized, doubleblind, placebo-controlled trial conducted in Germany,investigators reported that polyunsaturated PC helpedsupport liver health by promoting healthy plasma alanineaminotransferase activity and was well tolerated. This moleculealso plays a significant role in the healthy transport andmetabolism of lipids and lipid carrier molecules. Arandomized, double blind, placebo-controlled trialsuggested that oral lecithin supplementation may helpsupport healthy hepatic fat metabolism by providing asource of choline. Animal studies also report that soybeanPC may promote healthy lipid metabolism in theliver. Additional animal studies indicate that PC promoteshealthy liver and pancreatic antioxidant activity.Cognitive Support: PC has been studied in the context ofcognitive support and moderating stress. A long-termdouble blind placebo-controlled trial suggested that highdose soy lecithin may reduce mild memory loss associatedwith aging. A more recent animal study provided dataindicating that oral lecithin supplementation helpedsupport plasma choline levels, which was linked to anadaptogenic effect when the animals were exposed tovarious stresses. Ingredients:
Formula (#PH6)
Each Softgel capsule contains:
phosphatidylcholine 420 mg.(from 1,200 mg of soy lecithin concentrate)other ingredients: gelatin, glycerin)
Servings:
Pure Encapsulations recommends 2-8 capsules per day,in divided doses, with meals.
Caution:
If pregnant or lactating, consult your physician beforetaking this product. At several grams per day, somepeople may experience abdominal discomfort, diarrhea,or nausea.
At this time, there are no known adverse reactions whentaken in conjunction with medications.
Disclaimer:
The Food and Drug Administration has not evaluated statements contained herein. These products are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication.
References:
- Kumar R, Divekar HM, Gupta V, Srivastava KK. Antistress and adaptogenicactivity of lecithin supplementation. J Altern Complement Med.2002Aug;8(4):487-92.
- Mourelle M, Guarner F, Malagelada JR. Polyunsaturated phosphatidylcholineprevents stricture formation in a rat model of colitis.Gastroenterology. 1996 Apr;110(4):1093-7.
- Niederau C, Strohmeyer G, Heintges T, Peter K, Gopfert E.Polyunsaturated phosphatidyl-choline and interferon alpha for treatment ofchronic hepatitis B and C: a multi-center, randomized, double-blind, placebo-controlled trial. Hepatogastroenterology. 1998 May-Jun;45(21):797-804.
- Mastellone I I, Polichetti E, Gres S, de la Maisonneuve C, Domingo N,Marin V V, Lorec A, Farnarier C, Portugal H, Kaplanski G, Chanussot F.Dietary soybean phosphatidylcholines lower lipidemia: mechanisms at thelevels of intestine, endothelial cell, and hepato-biliary axis. J Nutr Biochem.2000 Sep 1;11(9):461-466.
- Little A, Levy R, Chuaqui-Kidd P, Hand D. A double-blind, placebo controlledtrial of high-dose lecithin in Alzheimer's disease. J NeurolNeurosurg Psychiatry. 1985 Aug;48(8):736-42.
- Aleynik SI, Leo MA, Aleynik MK, Lieber CS. Alcohol-induced pancreaticoxidative stress: protection by phospholipid repletion. Free Radic Biol Med.1999 Mar;26(5-6):609-19.
- Buchman AL, Dubin M, Jenden D, Moukarzel A, Roch MH, Rice K,Gornbein J, Ament ME, Eckhert CD. Lecithin increases plasma free cholineand decreases hepatic steatosis in long-term total parenteral nutritionpatients. Gastroenterology. 1992 Apr;102(4 Pt 1):1363-70.
- Healthnotes Clinical Essentials. Copyright 2004. Healthnotes, Inc.
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